New article in Kidney International about AT1 receptor antibodies in kidney transplant recipients

Read the abstract of this interesting article: Anti-angiotensin II type 1 receptor (AT1R) antibodies have been associated with allograft rejection. We hypothesized that circulating AT1R antibodies might identify kidney transplant recipients at increased risk of allograft rejection and loss who are not identified by the HLA system. We prospectively enrolled 1845 kidney transplant recipients from…

New publication in Frontiers in Bioscience about: Anti-ß1-Adrenoreceptor auto-Antibodies in elderly heart failure patients.

Abstract of the article: An autoimmune reaction directed against the cardiac b1-adrenergic receptor (beta1-ADR) leading to the generation of autoantibodies (AA) against this G-coupled receptor has been described in patients with heart failure (HF). Agonist-like beta1-ADR-AA are associated with morbidity in HF patients and even predict mortality. Standardised and valid diagnostic tools to detect beta…

new publication about Beta-1-Adrenergic Receptor Antibodies in Acute Coronary Syndrome

Beta-1-Adrenergic Receptor Antibodies in Acute Coronary Syndrome: Is Less Sometimes More?   Cardiovascular diseases are common, accounting for approximately 17.3 million global deaths annually. Substantial evidence exists for numerous risk factors including dyslipidemia, smoking, arterial hypertension, diabetes, and abdominal obesity. Numerous biomarkers have previously been reported in acute coronary syndromes, relating to both inflammation or…

CellTrend received the Patent for DIAGNOSIS OF CANCER BY DETECTING AUTO-ANTIBODIES AGAINST EGF-RECEPTOR

The results of the present Examples show that anti-EGFR antibody levels are significant lower in patients with ovarian cancer compared to healthy controls. Furthermore, the levels are significantly higher in patients in which show no relapse after treatment with chemotherapeutic agents or an inhibitor of EGFR activity. Levels of anti-EGFR antibody in patients suffering from…