The results of the present Examples show that anti-EGFR antibody levels are significant lower in patients with ovarian cancer compared to healthy controls. Furthermore, the levels are significantly higher in patients in which show no relapse after treatment with chemotherapeutic agents or an inhibitor of EGFR activity. Levels of anti-EGFR antibody in patients suffering from an ovarian cancer with serous histopathology are higher compared to samples from patients suffering from ovarian cancer with non-serous histopathology. Levels of anti-EGFR antibodies in samples are a well suited predictor for the response to the treatment with an angiogenesis inhibitor. Relapse of cancer or mortality of the EP 3 102 944 B1 18 5 10 15 20 25 30 35 40 45 50 55 patient as endpoints of the treatment can be predicted with a high degree of specificity and sensitivity